Instructional designers are the ones who create diverse styles of unique instructional courses that are meant for e-learning purposes. E-learning has become a reality in the present world, and the impact of the same can be witnessed in almost all principal arenas of human interests. The functional base of these e-learning processes is created by the instructional designers. They make use of the modern technological tools and formulate inventive instructional design to suit the varied requirements and the targeted audience. In our time, when the real relevance of e-learning and the constant development that occurs in the technological arena are taken into account, instructional designers have a significant role to play. However, the process of instructional design creation will have to be done with care, as the e-learning arena is a bit new to the general consumer. Instructional designers must apply practical sense while elearning course development; this is one of the existing instructional design challenges. The knowledge level of the targeted audience must be comprehended first, and only on that basis, novel instructional designs should be created.